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Details on Person HIP1(1-963)-p-7Y-ALK(1058-1620) fusion [cytosol]

Class:Id	EntityWithAccessionedSequence:9711975
_displayName	HIP1(1-963)-p-7Y-ALK(1058-1620) fusion [cytosol]
_timestamp	2023-03-30 12:08:48
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9711957] Rothfels, Karen, 2021-01-13
crossReference	[DatabaseIdentifier:9711745] COSMIC:COSF1620
disease	[Disease:1981182] lung squamous cell carcinoma
endCoordinate	963
hasModifiedResidue	[FragmentInsertionModification:9711916] Insertion of residues 1058 to 1620 at 964 from UniProt:Q9UM73 ALK [ModifiedResidue:9699796] O4'-phospho-L-tyrosine at 1096 [ModifiedResidue:9699868] O4'-phospho-L-tyrosine at 1278 [ModifiedResidue:9699844] O4'-phospho-L-tyrosine at 1282 [ModifiedResidue:9699911] O4'-phospho-L-tyrosine at 1283 [ModifiedResidue:9699876] O4'-phospho-L-tyrosine at 1359 [ModifiedResidue:9699886] O4'-phospho-L-tyrosine at 1507 [ModifiedResidue:9699803] O4'-phospho-L-tyrosine at 1604
literatureReference	[LiteratureReference:9711777] HIP1-ALK, a novel ALK fusion variant that responds to crizotinib
modified	[InstanceEdit:9832284] Orlic-Milacic, Marija, 2023-03-30
name	HIP1(1-963)-p-7Y-ALK(1058-1620) fusion Huntingtin-interacting protein 1 HIP1_HUMAN
referenceEntity	[ReferenceGeneProduct:56526] UniProt:O00291 HIP1 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9711987] R-HSA-9711975.2
startCoordinate	1
(hasComponent)	[Complex:9712026] HIP1(1-963)-p-7Y ALK(1058-1620) fusion dimer [cytosol] [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9905914] Update Tracker - [EntityWithAccessionedSequence:9711975] HIP1(1-963)-p-7Y-ALK(1058-1620) fusion [cytosol] - v85:[modifyName]
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No pathways have been reviewed or authored by HIP1(1-963)-p-7Y-ALK(1058-1620) fusion [cytosol] (9711975)