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Details on Person IRS:ALK fusion proteins [cytosol]

Class:Id	Complex:9711940
_displayName	IRS:ALK fusion proteins [cytosol]
_timestamp	2021-01-26 00:58:49
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9711934] Rothfels, Karen, 2021-01-13
disease	[Disease:1500689] cancer
hasComponent	[EntityWithAccessionedSequence:74769] IRS1 [cytosol] [Homo sapiens] [CandidateSet:9713536] IRS- and FRS-binding ALK fusion proteins [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9699651] Characterization of the transforming activity of p80, a hyperphosphorylated protein in a Ki-1 lymphoma cell line with chromosomal translocation t(2;5)
modified	[InstanceEdit:9713546] Rothfels, Karen, 2021-01-26
name	IRS:ALK fusion proteins
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9711950] R-HSA-9711940.1
(input)	[Reaction:9712082] ALK fusions phosphorylate IRS1 [Homo sapiens]
(output)	[Reaction:9712088] ALK fusion proteins bind IRS [Homo sapiens]
(physicalEntity)	[CatalystActivity:9711936] protein tyrosine kinase activity of IRS:ALK fusion proteins [cytosol]
(updatedInstance)	[_UpdateTracker:9902466] Update Tracker - [Complex:9711940] IRS:ALK fusion proteins [cytosol] - v78:[updateContainedComponent]
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No pathways have been reviewed or authored by IRS:ALK fusion proteins [cytosol] (9711940)