Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
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Details on Person IRS1 is phosphorylated downstream of NPM-ALK fusions (Fujimo...
| Class:Id | Summation:9711764 |
|---|---|
| _displayName | IRS1 is phosphorylated downstream of NPM-ALK fusions (Fujimo... |
| _timestamp | 2021-01-13 21:36:40 |
| created | [InstanceEdit:9711762] Rothfels, Karen, 2021-01-13 |
| text | IRS1 is phosphorylated downstream of NPM-ALK fusions (Fujimoto et al, 1996). ALK-dependent IRS phosphorylation activates the MAP kinase signaling pathway and promotes cellular proliferation, but direct binding of a RAS GEF such as GRB2:SOS1 has not been shown (reviewed in Chiarle et al, 2008; Roskoski, 2013). |
| (summation) | [Reaction:9712082] ALK fusions phosphorylate IRS1 [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by IRS1 is phosphorylated downstream of NPM-ALK fusions (Fujimo... (9711764)
