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Details on Person TPM4(2-222)insV-ALK(1059-1620) fusion [cytosol]

Class:IdEntityWithAccessionedSequence:9710851
_displayNameTPM4(2-222)insV-ALK(1059-1620) fusion [cytosol]
_timestamp2023-04-02 10:20:40
compartment[Compartment:70101] cytosol
created[InstanceEdit:9710843] Rothfels, Karen, 2021-01-05
crossReference[DatabaseIdentifier:9713346] COSMIC:COSF441
disease[Disease:9701987] inflammatory myofibroblastic tumor
endCoordinate222
hasModifiedResidue[FragmentInsertionModification:9710844] Insertion of residues 1059 to 1620 at 223 from UniProt:Q9UM73 ALK
[FragmentReplacedModification:9710849] Replacement of residues 222 to 222 by EV
literatureReference[LiteratureReference:9710811] TPM3-ALK and TPM4-ALK oncogenes in inflammatory myofibroblastic tumors
modified[InstanceEdit:9713442] Rothfels, Karen, 2021-01-26
[InstanceEdit:9730948] Rothfels, Karen, 2021-05-12
[InstanceEdit:9832533] Orlic-Milacic, Marija, 2023-04-02
nameTPM4(2-222)insV-ALK(1059-1620) fusion
Tropomyosin alpha-4 chain
TPM4_HUMAN
referenceEntity[ReferenceGeneProduct:66303] UniProt:P67936 TPM4 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9710856] R-HSA-9710851.2
startCoordinate2
(hasComponent)[Complex:9710895] TPM4(2-221)-ALK(1059-1620) fusion dimer [cytosol] [Homo sapiens]
(hasMember)[CandidateSet:9700080] ALK fusion proteins [cytosol] [Homo sapiens]
(updatedInstance)[_UpdateTracker:9905433] Update Tracker - [EntityWithAccessionedSequence:9710851] TPM4(2-222)insV-ALK(1059-1620) fusion [cytosol] - v85:[modifyEndCoordinate, modifyName]
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No pathways have been reviewed or authored by TPM4(2-222)insV-ALK(1059-1620) fusion [cytosol] (9710851)
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