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Details on Person EEF1G(1-343)-p-6Y-ALK(1106-1620) fusion [cytosol]

Class:Id	EntityWithAccessionedSequence:9710850
_displayName	EEF1G(1-343)-p-6Y-ALK(1106-1620) fusion [cytosol]
_timestamp	2023-03-30 17:41:25
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9710843] Rothfels, Karen, 2021-01-05
disease	[Disease:9699595] anaplastic large cell lymphoma
endCoordinate	343
hasModifiedResidue	[FragmentInsertionModification:9710836] Insertion of residues 1106 to 1620 at 344 from UniProt:Q9UM73 ALK [ModifiedResidue:9699868] O4'-phospho-L-tyrosine at 1278 [ModifiedResidue:9699844] O4'-phospho-L-tyrosine at 1282 [ModifiedResidue:9699911] O4'-phospho-L-tyrosine at 1283 [ModifiedResidue:9699876] O4'-phospho-L-tyrosine at 1359 [ModifiedResidue:9699886] O4'-phospho-L-tyrosine at 1507 [ModifiedResidue:9699803] O4'-phospho-L-tyrosine at 1604
literatureReference	[LiteratureReference:9710762] Anaplastic lymphoma kinase-positive anaplastic large cell lymphoma with the variant RNF213-, ATIC- and TPM3-ALK fusions is characterized by copy number gain of the rearranged ALK gene
modified	[InstanceEdit:9832399] Orlic-Milacic, Marija, 2023-03-30
name	EEF1G(1-343)-p-6Y-ALK(1106-1620) fusion Elongation factor 1-gamma EF1G_HUMAN
referenceEntity	[ReferenceGeneProduct:54174] UniProt:P26641 EEF1G [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9710866] R-HSA-9710850.2
startCoordinate	2
(hasComponent)	[Complex:9710881] EEF1G(1-343)-6Y ALK(1106-1620) fusion dimer [cytosol] [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9905496] Update Tracker - [EntityWithAccessionedSequence:9710850] EEF1G(1-343)-p-6Y-ALK(1106-1620) fusion [cytosol] - v85:[modifyName]
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No pathways have been reviewed or authored by EEF1G(1-343)-p-6Y-ALK(1106-1620) fusion [cytosol] (9710850)