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Details on Person TPM3(2-258)insV-ALK(1059-1620) fusion [cytosol]

Class:IdEntityWithAccessionedSequence:9710848
_displayNameTPM3(2-258)insV-ALK(1059-1620) fusion [cytosol]
_timestamp2023-04-02 10:24:21
compartment[Compartment:70101] cytosol
created[InstanceEdit:9710843] Rothfels, Karen, 2021-01-05
crossReference[DatabaseIdentifier:9713341] COSMIC:COSF439
disease[Disease:9699595] anaplastic large cell lymphoma
[Disease:9701987] inflammatory myofibroblastic tumor
endCoordinate258
hasModifiedResidue[FragmentInsertionModification:9710831] Insertion of residues 1059 to 1620 at 259 from UniProt:Q9UM73 ALK
[FragmentReplacedModification:9710846] Replacement of residues 258 to 258 by EV
literatureReference[LiteratureReference:9710718] A new fusion gene TPM3-ALK in anaplastic large cell lymphoma created by a (1;2)(q25;p23) translocation
[LiteratureReference:9710811] TPM3-ALK and TPM4-ALK oncogenes in inflammatory myofibroblastic tumors
modified[InstanceEdit:9713441] Rothfels, Karen, 2021-01-26
[InstanceEdit:9730947] Rothfels, Karen, 2021-05-12
[InstanceEdit:9832534] Orlic-Milacic, Marija, 2023-04-02
nameTPM3(2-258)insV-ALK(1059-1620) fusion
Tropomyosin alpha-3 chain
TPM3_HUMAN
referenceEntity[ReferenceGeneProduct:66301] UniProt:P06753 TPM3 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9710855] R-HSA-9710848.2
startCoordinate2
(hasComponent)[Complex:9710892] TPM3(2-258)-ALK(1059-1620) fusion dimer [cytosol] [Homo sapiens]
(hasMember)[CandidateSet:9700080] ALK fusion proteins [cytosol] [Homo sapiens]
(updatedInstance)[_UpdateTracker:9905251] Update Tracker - [EntityWithAccessionedSequence:9710848] TPM3(2-258)insV-ALK(1059-1620) fusion [cytosol] - v85:[modifyName]
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No pathways have been reviewed or authored by TPM3(2-258)insV-ALK(1059-1620) fusion [cytosol] (9710848)
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