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Details on Person CLTC(2-1634)insDGVSSVTQAGVQWRDLGSLQPSRARLPGHVAADHPPA-p-7Y-ALK(1058-1620) fusion [cytosol]

Class:Id	EntityWithAccessionedSequence:9710835
_displayName	CLTC(2-1634)insDGVSSVTQAGVQWRDLGSLQPSRARLPGHVAADHPPA-p-7Y-ALK(1058-1620) fusion [cytosol]
_timestamp	2023-04-02 09:36:10
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9710843] Rothfels, Karen, 2021-01-05
disease	[Disease:9632617] diffuse large B-cell lymphoma
endCoordinate	1634
hasModifiedResidue	[FragmentInsertionModification:9710845] Insertion of residues 1058 to 1620 at 1635 from UniProt:Q9UM73 ALK [FragmentReplacedModification:9710838] Replacement of residues 1634 to 1634 by YDGVSSVTQAGVQWRDLGSLQPSRARLPGHVAADHPPA [ModifiedResidue:9699868] O4'-phospho-L-tyrosine at 1278 [ModifiedResidue:9699844] O4'-phospho-L-tyrosine at 1282 [ModifiedResidue:9699911] O4'-phospho-L-tyrosine at 1283 [ModifiedResidue:9699796] O4'-phospho-L-tyrosine at 1096 [ModifiedResidue:9699876] O4'-phospho-L-tyrosine at 1359 [ModifiedResidue:9699886] O4'-phospho-L-tyrosine at 1507 [ModifiedResidue:9699803] O4'-phospho-L-tyrosine at 1604
literatureReference	[LiteratureReference:9710725] ALK activation by the CLTC-ALK fusion is a recurrent event in large B-cell lymphoma
modified	[InstanceEdit:9832322] Orlic-Milacic, Marija, 2023-03-30 [InstanceEdit:9832524] Orlic-Milacic, Marija, 2023-04-02
name	CLTC(2-1634)insDGVSSVTQAGVQWRDLGSLQPSRARLPGHVAADHPPA-p-7Y-ALK(1058-1620) fusion fullName evidence="36 37"Clathrin heavy chain 1 CLH1_HUMAN
referenceEntity	[ReferenceGeneProduct:405001] UniProt:Q00610 CLTC [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9710860] R-HSA-9710835.2
startCoordinate	2
(hasComponent)	[Complex:9710879] CLTC(2-1634)-p-7Y ALK(1058-1620) fusion dimer [cytosol] [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9905695] Update Tracker - [EntityWithAccessionedSequence:9710835] CLTC(2-1634)insDGVSSVTQAGVQWRDLGSLQPSRARLPGHVAADHPPA-p-7Y-ALK(1058-1620) fusion [cytosol] - v85:[modifyName]
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No pathways have been reviewed or authored by CLTC(2-1634)insDGVSSVTQAGVQWRDLGSLQPSRARLPGHVAADHPPA-p-7Y-ALK(1058-1620) fusion [cytosol] (9710835)