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Details on Person CO binds to Cytochrome c oxidase

Class:Id	Reaction:9709406
_displayName	CO binds to Cytochrome c oxidase
_doRelease	TRUE
_timestamp	2021-01-29 10:53:17
authored	[InstanceEdit:9708955] Stephan, Ralf, 2020-12-03
compartment	[Compartment:70616] mitochondrial inner membrane
created	[InstanceEdit:9709348] Stephan, Ralf, 2020-12-14
edited	[InstanceEdit:9708955] Stephan, Ralf, 2020-12-03
input	[Complex:164316] Cytochrome c oxidase [mitochondrial inner membrane] [Homo sapiens] [SimpleEntity:9709326] CO [mitochondrial inner membrane]
isChimeric	FALSE
literatureReference	[LiteratureReference:9709392] Carbon monoxide signals via inhibition of cytochrome c oxidase and generation of mitochondrial reactive oxygen species [LiteratureReference:9709343] Carbon monoxide specifically inhibits cytochrome c oxidase of human mitochondrial respiratory chain [LiteratureReference:9709410] Crystal structure of CO-bound cytochrome c oxidase determined by serial femtosecond X-ray crystallography at room temperature
modified	[InstanceEdit:9713665] Stephan, Ralf, 2021-01-29 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	CO binds to Cytochrome c oxidase
output	[Complex:9709412] Cytochrome c oxidase:CO [mitochondrial inner membrane] [Homo sapiens]
precedingEvent	[BlackBoxEvent:9709366] CO translocates from cytosol to mitochondrial inner membrane [Homo sapiens] [Reaction:189398] HMOX1 dimer, HMOX2 cleave heme [Homo sapiens]
releaseDate	2021-03-23
reviewed	[InstanceEdit:9713327] Somers, Julia, 2021-01-23
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9709435] R-HSA-9709406.2
summation	[Summation:9709407] Carbon monoxide (CO) toxicity is the result of a combination...
(hasEvent)	[Pathway:9707564] Cytoprotection by HMOX1 [Homo sapiens]
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No pathways have been reviewed or authored by CO binds to Cytochrome c oxidase (9709406)