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Details on Person H2O2 reduces MetHb

Class:Id	Reaction:9709360
_displayName	H2O2 reduces MetHb
_doRelease	TRUE
_timestamp	2021-01-29 10:54:32
authored	[InstanceEdit:9708955] Stephan, Ralf, 2020-12-03
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:9709348] Stephan, Ralf, 2020-12-14
edited	[InstanceEdit:9708955] Stephan, Ralf, 2020-12-03
input	[SimpleEntity:351629] H2O2 [extracellular region] [SimpleEntity:351629] H2O2 [extracellular region] [SimpleEntity:351629] H2O2 [extracellular region] [SimpleEntity:351629] H2O2 [extracellular region] [Complex:2168866] MetHb [extracellular region] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9709427] Carbon monoxide promotes respiratory hemoproteins iron reduction using peroxides as electron donors
modified	[InstanceEdit:9709902] Stephan, Ralf, 2020-12-18 [InstanceEdit:9713665] Stephan, Ralf, 2021-01-29 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	H2O2 reduces MetHb
output	[Complex:9707672] ferrohemoglobin [extracellular region] [Homo sapiens] [SimpleEntity:109276] H2O [extracellular region] [SimpleEntity:109276] H2O [extracellular region] [SimpleEntity:109276] H2O [extracellular region] [SimpleEntity:109276] H2O [extracellular region] [SimpleEntity:352327] O2 [extracellular region] [SimpleEntity:352327] O2 [extracellular region]
precedingEvent	[Reaction:9707504] H2O2 oxidises ferrohemoglobin to MetHb [Homo sapiens] [BlackBoxEvent:9709396] CO translocates from cytosol to extracellular region [Homo sapiens] [Reaction:189398] HMOX1 dimer, HMOX2 cleave heme [Homo sapiens]
releaseDate	2021-03-23
reviewed	[InstanceEdit:9713327] Somers, Julia, 2021-01-23
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9709436] R-HSA-9709360.2
summation	[Summation:9709345] Hydrogen peroxide (H2O2) can reduce methemoglobin (metHb) bu...
(hasEvent)	[Pathway:9707564] Cytoprotection by HMOX1 [Homo sapiens]
(precedingEvent)	[Reaction:9709317] CO binds to free ferrohemoglobin [Homo sapiens] [NegativePrecedingEvent:9767162] Futile Cycle: H2O2 reduces MetHb
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No pathways have been reviewed or authored by H2O2 reduces MetHb (9709360)