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Details on Person DHFR dimer reduces FOLA to DHF

Class:IdReaction:9709098
_displayNameDHFR dimer reduces FOLA to DHF
_doReleaseTRUE
_timestamp2021-03-01 09:33:48
authored[InstanceEdit:197987] Jassal, B, 2007-05-16 09:27:22
catalystActivity[CatalystActivity:9709122] folate reductase activity of DHFR dimer [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:9709130] Jassal, Bijay, 2020-12-10
edited[InstanceEdit:9709130] Jassal, Bijay, 2020-12-10
input[SimpleEntity:197965] FOLA [cytosol]
[SimpleEntity:29364] NADPH [cytosol]
[SimpleEntity:70106] H+ [cytosol]
literatureReference[LiteratureReference:197975] The functional human dihydrofolate reductase gene
[LiteratureReference:200699] Crystal structures of recombinant human dihydrofolate reductase complexed with folate and 5-deazafolate
modified[InstanceEdit:9716830] Jassal, Bijay, 2021-03-01
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameDHFR dimer reduces FOLA to DHF
output[SimpleEntity:73604] DHF [cytosol]
[SimpleEntity:29366] NADP+ [cytosol]
precedingEvent
releaseDate2007-08-21
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9709160] R-HSA-9709098.2
summation[Summation:9709095] Cytosolic, dimeric dihydrofolate reductase (DHFR dimer) cata...
(hasEvent)[Pathway:196757] Metabolism of folate and pterines [Homo sapiens]
(precedingEvent)[Reaction:197972] DHF is reduced to tetrahydrofolate (THF) [Homo sapiens]
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No pathways have been reviewed or authored by DHFR dimer reduces FOLA to DHF (9709098)
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