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Details on Person Stephan, Ralf, 2020-11-30
| Class:Id | InstanceEdit:9708449 |
| _displayName | Stephan, Ralf, 2020-11-30 |
| _timestamp | 2020-11-30 10:15:18 |
| author | [Person:804962] Stephan, Ralf |
| dateTime | 2020-11-30 10:12:47 |
| (created) | [Complex:9708443] BACH1:FBXL17:SCF (SKP2) [nucleoplasm] [Homo sapiens] [LiteratureReference:9708444] Isolation of the human BACH1 transcription regulator gene, which maps to chromosome 21q22.1 [CatalystActivity:9708445] aspartic endopeptidase activity, intramembrane cleaving of HM13 [endoplasmic reticulum membrane] [Person:9708446] Weng, Yi-Hao [RegulationReference:9708447] Positive gene expression regulation by 'p-NFE2L2 [nucleoplasm]' Regulation of the antioxidant response element by protein kinase C-mediated phosphorylation of NF-E2-related factor 2 [RegulationReference:9708448] Negative gene expression regulation by 'let-7 microRNA [cytosol]' The let-7 microRNA enhances heme oxygenase-1 by suppressing Bach1 and attenuates oxidant injury in human hepatocytes [Person:9708450] Yanagawa, T [LiteratureReference:9708451] Insights into the mechanism of isoenzyme-specific signal peptide peptidase-mediated translocation of heme oxygenase [Person:9708452] Bordner, Jessica [Person:9708453] Guo, Jieyu |
| (modified) | [Reaction:8932284] PKC phosphorylates NFE2L2 [Homo sapiens] [BlackBoxEvent:8932309] NFE2L2 translocates from cytosol to nucleoplasm [Homo sapiens] [Summation:8932313] The KEAP1:CUL3:RBX1 E3-ubiquitin ligase complex is a negativ... [BlackBoxEvent:8932322] CK2 phosphorylates NFE2L2 [Homo sapiens] [Summation:8932323] Upon stimulation by oxidative/electrophilic stress, Nuclear ... [Reaction:8932327] NFE2L2 binds KEAP1:NEDD8-CUL3:RBX1 [Homo sapiens] [Summation:8932337] Under the basal resting conditions, cytosolic Nuclear factor... [Summation:8932343] Ubiquitinated Nuclear factor erythroid 2-related (NFE2L2) un... [BlackBoxEvent:8932355] 26S proteasome degrades Ub-NFE2L2 [Homo sapiens] [Summation:8932357] In response to oxidative stress, protein kinase C (PKC) phos... |
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No pathways have been reviewed or authored by Stephan, Ralf, 2020-11-30 (9708449)