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Details on Person DICER1 cleaves tRNA Lys TTT 3 in tRNA:HIV RNA hybrid

Class:IdBlackBoxEvent:9708408
_displayNameDICER1 cleaves tRNA Lys TTT 3 in tRNA:HIV RNA hybrid
_doReleaseTRUE
_timestamp2021-02-23 18:15:18
authored[InstanceEdit:9708406] May, Bruce, 2020-11-29
catalystActivity[CatalystActivity:9708322] ribonuclease III activity of DICER1 [cytosol]
compartment[Compartment:70101] cytosol
created[InstanceEdit:9708416] May, Bruce, 2020-11-29
disease[Disease:1660559] Human immunodeficiency virus infectious disease
edited[InstanceEdit:9708406] May, Bruce, 2020-11-29
input[Complex:173798] HIV-1 RNA template:tRNA primer [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9708407] Pyrosequencing of small non-coding RNAs in HIV-1 infected cells: evidence for the processing of a viral-cellular double-stranded RNA hybrid
modified[InstanceEdit:9709030] May, Bruce, 2020-12-06
[InstanceEdit:9714722] May, Bruce, 2021-02-13
[InstanceEdit:9716368] May, Bruce, 2021-02-20
[InstanceEdit:9716673] May, Bruce, 2021-02-23
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameDICER1 cleaves tRNA Lys TTT 3 in tRNA:HIV RNA hybrid
output[EntityWithAccessionedSequence:9708409] tRNA Lys TTT (56-73) [cytosol] [Homo sapiens]
relatedSpecies[Species:164493] Human immunodeficiency virus 1
releaseDate2021-03-23
reviewed[InstanceEdit:9714721] Basso, Katia, 2021-02-13
[InstanceEdit:9716353] Dutta, Anindya, 2021-02-20
[InstanceEdit:9716320] Su, Zhangli, 2021-02-20
[InstanceEdit:9716363] Wilson, Briana, 2021-02-20
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9708419] R-HSA-9708408.2
summation[Summation:9709024] DICER1 cleaves the double-stranded RNA hybrid formed by the ...
(hasEvent)[Pathway:9708296] tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis [Homo sapiens]
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