Reactome: A Curated Pathway Database
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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

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Details on Person SOCS1 and SOCS3 recruit Elongin B (ELOB), Elongin C (ELOC), ...

Class:IdSummation:9707974
_displayNameSOCS1 and SOCS3 recruit Elongin B (ELOB), Elongin C (ELOC), ...
_timestamp2020-11-21 05:07:23
created[InstanceEdit:9707968] May, Bruce, 2020-11-21
textSOCS1 and SOCS3 recruit Elongin B (ELOB), Elongin C (ELOC), Cullin5 (CUL5), and RNF7 to CSF3R to form a ubiquitin E3 ligase complex (Kamura et al. 2004 and inferred from mouse homologs). SOCS3 has 100-fold higher affinity for CUL5 than SOCS1 has (inferred from mouse homologs).
(summation)[Reaction:9705729] SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 binds CUL5, ELOB, ELOC, RNF7 [Homo sapiens]
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No pathways have been reviewed or authored by SOCS1 and SOCS3 recruit Elongin B (ELOB), Elongin C (ELOC), ... (9707974)