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Query author contributions in Reactome

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Details on Person Socs1,3:p-4Y-Csf3r:Csf3 dimer:Lyn:p-Y-Jak1:p-Jak2:p-Syk:p-Hck:p-Tyk2 binds Cul5, EloB, EloC, and Rnf7

Class:IdReaction:9707972
_displayNameSocs1,3:p-4Y-Csf3r:Csf3 dimer:Lyn:p-Y-Jak1:p-Jak2:p-Syk:p-Hck:p-Tyk2 binds Cul5, EloB, EloC, and Rnf7
_doReleaseTRUE
_timestamp2020-12-12 08:34:57
authored[InstanceEdit:9707978] May, Bruce, 2020-11-09
compartment[Compartment:24337] endocytic vesicle membrane
created[InstanceEdit:9707968] May, Bruce, 2020-11-21
edited[InstanceEdit:9707978] May, Bruce, 2020-11-09
input[Complex:9707916] Socs1,3:p-4Y-Csf3r:Csf3 dimer:Lyn:p-Y-Jak1:p-Jak2:p-Syk:p-Hck:p-Tyk2 [endocytic vesicle membrane] [Mus musculus]
[EntityWithAccessionedSequence:9707897] Cul5 [cytosol] [Mus musculus]
[EntityWithAccessionedSequence:9707897] Cul5 [cytosol] [Mus musculus]
[EntityWithAccessionedSequence:9707901] Elob [cytosol] [Mus musculus]
[EntityWithAccessionedSequence:9707901] Elob [cytosol] [Mus musculus]
[EntityWithAccessionedSequence:9707914] Eloc [cytosol] [Mus musculus]
[EntityWithAccessionedSequence:9707914] Eloc [cytosol] [Mus musculus]
[EntityWithAccessionedSequence:9707924] Rnf7 [cytosol] [Mus musculus]
[EntityWithAccessionedSequence:9707924] Rnf7 [cytosol] [Mus musculus]
isChimericFALSE
literatureReference[LiteratureReference:9707874] The SOCS box encodes a hierarchy of affinities for Cullin5: implications for ubiquitin ligase formation and cytokine signalling suppression
[LiteratureReference:9707893] The SOCS box domain of SOCS3: structure and interaction with the elonginBC-cullin5 ubiquitin ligase
[LiteratureReference:9707887] Reconstruction of an active SOCS3-based E3 ubiquitin ligase complex in vitro: identification of the active components and JAK2 and gp130 as substrates
modified[InstanceEdit:9709305] May, Bruce, 2020-12-12
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameSocs1,3:p-4Y-Csf3r:Csf3 dimer:Lyn:p-Y-Jak1:p-Jak2:p-Syk:p-Hck:p-Tyk2 binds Cul5, EloB, EloC, and Rnf7
output[Complex:9707918] Socs1,3:p-4Y-Csf3r:Csf3 dimer:Lyn:p-Y-Jak1:p-Jak2:p-Syk:p-Hck:p-Tyk2:Cul5:EloB:EloC:Rnf7 [endocytic vesicle membrane] [Mus musculus]
releaseDate2021-03-23
reviewed[InstanceEdit:9709304] Touw, Ivo P, 2020-12-12
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48892] Mus musculus
stableIdentifier[StableIdentifier:9707984] R-MMU-9707972.2
summation[Summation:9707967] Socs1 and Socs3 recruit Elongin B (Elob), Elongin C (Eloc), ...
(inferredFrom)[Reaction:9705729] SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 binds CUL5, ELOB, ELOC, RNF7 [Homo sapiens]
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No pathways have been reviewed or authored by Socs1,3:p-4Y-Csf3r:Csf3 dimer:Lyn:p-Y-Jak1:p-Jak2:p-Syk:p-Hck:p-Tyk2 binds Cul5, EloB, EloC, and Rnf7 (9707972)