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Details on Person Reconstruction of an active SOCS3-based E3 ubiquitin ligase complex in vitro: identification of the active components and JAK2 and gp130 as substrates

Class:IdLiteratureReference:9707887
_displayNameReconstruction of an active SOCS3-based E3 ubiquitin ligase complex in vitro: identification of the active components and JAK2 and gp130 as substrates
_timestamp2020-11-21 04:40:53
author[Person:9707886] Kershaw, Nadia J
[Person:9707889] Laktyushin, Artem
[Person:2672315] Nicola, Nicos A
[Person:5364149] Babon, Jeffrey J
created[InstanceEdit:9707884] May, Bruce, 2020-11-21
journalGrowth Factors
pages1-10
pubMedIdentifier24438103
titleReconstruction of an active SOCS3-based E3 ubiquitin ligase complex in vitro: identification of the active components and JAK2 and gp130 as substrates
volume32
year2014
(literatureReference)[Complex:9729683] SOCS3:ELOB:ELOC:CUL5:RNF7 [cytosol] [Homo sapiens]
[Reaction:9707972] Socs1,3:p-4Y-Csf3r:Csf3 dimer:Lyn:p-Y-Jak1:p-Jak2:p-Syk:p-Hck:p-Tyk2 binds Cul5, EloB, EloC, and Rnf7 [Mus musculus]
[Summation:9729682] A stable 1:1:1:1:1, SOCS3:ELOB:ELOC:CUL5:RNF7(RBX2)/RBX1 E3 ...
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