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Details on Person HMOX1 gene produces HMOX1 dimer
Class:Id BlackBoxEvent:9707645 _displayName HMOX1 gene produces HMOX1 dimer _doRelease TRUE _timestamp 2022-02-28 18:06:13 authored [InstanceEdit:9707640] Stephan, Ralf, 2020-11-12 compartment [Compartment:7660] nucleoplasm [Compartment:12045] endoplasmic reticulum membrane created [InstanceEdit:9707568] Stephan, Ralf, 2020-11-19 edited [InstanceEdit:9707640] Stephan, Ralf, 2020-11-12 input [EntityWithAccessionedSequence:6789487] HMOX1 gene [nucleoplasm] [Homo sapiens] isChimeric FALSE literatureReference [LiteratureReference:9707697] Bach1 functions as a hypoxia-inducible repressor for the heme oxygenase-1 gene in human cells [LiteratureReference:9707521] Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene modified [InstanceEdit:9707992] Stephan, Ralf, 2020-11-23 [InstanceEdit:9707995] Jassal, Bijay, 2020-11-23 [InstanceEdit:9708449] Stephan, Ralf, 2020-11-30 [InstanceEdit:9708934] Stephan, Ralf, 2020-12-03 [InstanceEdit:9713328] Stephan, Ralf, 2021-01-25 [InstanceEdit:9713665] Stephan, Ralf, 2021-01-29 [InstanceEdit:9716684] Jassal, Bijay, 2021-02-23 [InstanceEdit:9716695] Stephan, Ralf, 2021-02-24 [InstanceEdit:9767063] Rothfels, Karen, 2022-02-24 [InstanceEdit:9767547] Rothfels, Karen, 2022-02-28 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08 name HMOX1 gene produces HMOX1 dimer output [Complex:9706826] HMOX1 dimer [endoplasmic reticulum membrane] [Homo sapiens] precedingEvent
regulatedBy [NegativeGeneExpressionRegulation:9707541] Negative gene expression regulation by 'BACH1:MAFK [nucleoplasm]' [PositiveGeneExpressionRegulation:9767064] Positive gene expression regulation by 'P-NFE2L2:MAFK [nucleoplasm]' regulationReference [RegulationReference:9707518] Negative gene expression regulation by 'BACH1:MAFK [nucleoplasm]' Bach1 functions as a hypoxia-inducible repressor for the heme oxygenase-1 gene in human cells [RegulationReference:9767062] Positive gene expression regulation by 'P-NFE2L2:MAFK [nucleoplasm]' Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages releaseDate 2021-03-23 reviewed [InstanceEdit:9713327] Somers, Julia, 2021-01-23 [InstanceEdit:9766992] Cuadrado, Antonio, 2022-02-23 reviewStatus [ReviewStatus:9821382] five stars revised [InstanceEdit:9767061] Rothfels, Karen, 2022-02-24 species [Species:48887] Homo sapiens stableIdentifier [StableIdentifier:9707715] R-HSA-9707645.3 summation [Summation:9707503] Transcription regulator protein BACH1 is a critical physiolo... (hasEvent) [Pathway:9707587] Regulation of HMOX1 expression and activity [Homo sapiens] [Pathway:9707616] Heme signaling [Homo sapiens] (precedingEvent) [Reaction:189398] HMOX1 dimer, HMOX2 cleave heme [Homo sapiens] [Reaction:9708457] HM13 cleaves HMOX1 dimer [Homo sapiens] [BlackBoxEvent:9708558] HMOX1 dimer translocates from ER membrane to mitochondrial outer membrane [Homo sapiens] (updatedInstance) [_UpdateTracker:9774849] Update Tracker - [BlackBoxEvent:9707645] HMOX1 gene produces HMOX1 dimer - v80:[add_removeRegulator]
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