Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person Free heme initially binds to the lipoproteins LDL and HDL wh...

Class:IdSummation:9707527
_displayNameFree heme initially binds to the lipoproteins LDL and HDL wh...
_timestamp2021-01-11 10:20:34
created[InstanceEdit:9707568] Stephan, Ralf, 2020-11-19
literatureReference[LiteratureReference:2168824] Kinetics of hemin distribution in plasma reveals its role in lipoprotein oxidation
[LiteratureReference:9707633] Pro-oxidant and cytotoxic effects of circulating heme
modified[InstanceEdit:9707852] Stephan, Ralf, 2020-11-20
[InstanceEdit:9711048] Stephan, Ralf, 2021-01-11
textFree heme initially binds to the lipoproteins LDL and HDL which are highly susceptible to oxidation by ferriheme (FeHM). The half-life of the heme:lipoprotein complex is longer than 20 sec. Heme is then transferred to the antioxidants albumin and hemopexin (Miller and Shaklai, 1999; Jeney et al, 2002)
(summation)[Reaction:9707586] FeHM oxidises LDL,HDL [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by Free heme initially binds to the lipoproteins LDL and HDL wh... (9707527)