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Query author contributions in Reactome

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Details on Person RHOBTB3, like other RHOBTB family members, RHOBTB1 and RHOBT...

Class:IdSummation:9706394
_displayNameRHOBTB3, like other RHOBTB family members, RHOBTB1 and RHOBT...
_timestamp2020-11-04 13:57:57
created[InstanceEdit:9706397] Orlic-Milacic, Marija, 2020-11-04
modified[InstanceEdit:9706419] Orlic-Milacic, Marija, 2020-11-04
textRHOBTB3, like other RHOBTB family members, RHOBTB1 and RHOBTB2, binds CUL3 (cullin 3) a core component of BTB:CUL3:RBX1 E3 ubiquitin ligase complexes (Berthold et al. 2008). The following proteins are substrates of RHOBTB3-dependent ubiquitin ligase complexes:
RAB9A, RAB9B (Espinosa et al. 2009)
Cyclin E1 (Lu and Pfeffer 2013)
LRRC41 (MUF1) (Schenková et al. 2012).

The following proteins bind directly to RHOBTB3 but there is no evidence that they are substrates of RHOBTB3-dependent ubiquitin ligase complexes:
HGS (HRS) (Pridgeon et al. 2009)
PLIN3 (TIP47) (Espinosa et al. 2009)
5-HT7a serotonin receptor (Matthys et al. 2012)
VHL (Zhang et al. 2015).
(summation)[Reaction:9706390] RHOBTB3 binds interacting proteins at trans-Golgi network [Homo sapiens]
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No pathways have been reviewed or authored by RHOBTB3, like other RHOBTB family members, RHOBTB1 and RHOBT... (9706394)