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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person Active FLT3 binds to SOCS6

Class:IdReaction:9706330
_displayNameActive FLT3 binds to SOCS6
_doReleaseTRUE
_timestamp2020-11-06 20:52:59
authored[InstanceEdit:9706566] Rothfels, Karen, 2020-11-06
compartment[Compartment:876] plasma membrane
[Compartment:70101] cytosol
created[InstanceEdit:9706331] Rothfels, Karen, 2020-11-04
edited[InstanceEdit:9706566] Rothfels, Karen, 2020-11-06
input[Complex:9604751] Active FLT3 [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:1469969] SOCS6 [cytosol] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9706148] Suppressor of cytokine signaling 6 (SOCS6) negatively regulates Flt3 signal transduction through direct binding to phosphorylated tyrosines 591 and 919 of Flt3
[LiteratureReference:9706120] SOCS proteins in regulation of receptor tyrosine kinase signaling
modified[InstanceEdit:9706570] Rothfels, Karen, 2020-11-06
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameActive FLT3 binds to SOCS6
output[Complex:9706227] active FLT3:SOCS6 [plasma membrane] [Homo sapiens]
precedingEvent
releaseDate2020-12-08
reviewed[InstanceEdit:9706568] Kazi, Julhash U, 2020-11-06
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9706333] R-HSA-9706330.2
summation[Summation:9706332] The E3 ubiquitin ligase SOCS6 binds to tyrosine phosphorylat...
(hasEvent)[Pathway:9706369] Negative regulation of FLT3 [Homo sapiens]
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