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Details on Person Flt3-dependent transformation by inactivating c-Cbl mutations in AML

Class:IdLiteratureReference:9706100
_displayNameFlt3-dependent transformation by inactivating c-Cbl mutations in AML
_timestamp2020-11-04 12:15:36
author[Person:9695999] Sargin, Bülent
[Person:2581428] Choudhary, Chunaram
[Person:5655162] Crosetto, Nicola
[Person:9706101] Schmidt, Mirko H H
[Person:9691820] Grundler, Rebekka
[Person:9706103] Rensinghoff, Marion
[Person:9706104] Thiessen, Christine
[Person:9697799] Tickenbrock, Lara
[Person:9696002] Schwäble, Joachim
[Person:9697798] Brandts, Christian
[Person:9706105] August, Benjamin
[Person:9615456] Koschmieder, Steffen
[Person:9706102] Bandi, Srinivasa Rao
[Person:9649391] Duyster, Justus
[Person:8952087] Berdel, Wolfgang E
[Person:8952089] Müller-Tidow, Carsten
[Person:5228414] Dikic, Ivan
[Person:8952086] Serve, Hubert
created[InstanceEdit:9706099] Rothfels, Karen, 2020-11-04
journalBlood
pages1004-12
pubMedIdentifier17446348
titleFlt3-dependent transformation by inactivating c-Cbl mutations in AML
volume110
year2007
(literatureReference)[EntityWithAccessionedSequence:9706186] CBL R420Q [cytosol] [Homo sapiens]
[Reaction:9706293] Active FLT3 binds to CBL [Homo sapiens]
[Reaction:9706350] FLT3 phosphorylates CBL [Homo sapiens]
[BlackBoxEvent:9706354] Ubiquitination of FLT3 [Homo sapiens]
[FailedReaction:9706356] CBL mutants don't ubiquitinate FLT3 [Homo sapiens]
[BlackBoxEvent:9706364] Internalization of ubiquitinated FLT3 [Homo sapiens]
[Pathway:9706377] FLT3 signaling by CBL mutants [Homo sapiens]
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No pathways have been reviewed or authored by Flt3-dependent transformation by inactivating c-Cbl mutations in AML (9706100)