Query author contributions in Reactome

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Details on Person SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 is endocytosed

Class:Id	BlackBoxEvent:9705726
_displayName	SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 is endocytosed
_doRelease	TRUE
_timestamp	2020-12-12 08:34:07
authored	[InstanceEdit:9705725] May, Bruce, 2020-10-24
compartment	[Compartment:876] plasma membrane [Compartment:24337] endocytic vesicle membrane
created	[InstanceEdit:9705735] May, Bruce, 2020-10-30
edited	[InstanceEdit:9705725] May, Bruce, 2020-10-24
inferredFrom	[BlackBoxEvent:9707979] Socs1,3:p-4Y-Csf3r:Csf3 dimer:Lyn:p-Y-Jak1:p-Jak2:p-Syk:p-Hck:p-Tyk2 is endocytosed [Mus musculus]
input	[Complex:9705439] SOCS1,3:p-4Y-CSF3R:CSF3dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 [plasma membrane] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9707882] Receptor activation and 2 distinct COOH-terminal motifs control G-CSF receptor distribution and internalization kinetics [LiteratureReference:9707879] Defective internalization and sustained activation of truncated granulocyte colony-stimulating factor receptor found in severe congenital neutropenia/acute myeloid leukemia [LiteratureReference:9707892] Suppressor of cytokine signaling 3 controls lysosomal routing of G-CSF receptor
modified	[InstanceEdit:9707985] May, Bruce, 2020-11-21 [InstanceEdit:9709305] May, Bruce, 2020-12-12 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 is endocytosed
output	[Complex:9705731] SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 [endocytic vesicle membrane] [Homo sapiens]
precedingEvent	[Reaction:9705467] SOCS1,3 binds p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 [Homo sapiens] [BlackBoxEvent:9705466] p-Y-STAT1,3,5 dimer enhances expression of SOCS1 [Homo sapiens] [BlackBoxEvent:9705458] p-Y-STAT1,3,5 dimer enhances expression of SOCS3 [Homo sapiens]
releaseDate	2021-03-23
reviewed	[InstanceEdit:9709304] Touw, Ivo P, 2020-12-12
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9705758] R-HSA-9705726.2
summation	[Summation:9707976] After binding CSF3 (G-CSF), the CSF3 receptor CSF3R is inter...
(hasEvent)	[Pathway:9705462] Inactivation of CSF3 (G-CSF) signaling [Homo sapiens]
(precedingEvent)	[Reaction:9705729] SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 binds CUL5, ELOB, ELOC, RNF7 [Homo sapiens]
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No pathways have been reviewed or authored by SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 is endocytosed (9705726)