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Details on Person IKKε-mediated tumorigenesis requires K63-linked polyubiquitination by a cIAP1/cIAP2/TRAF2 E3 ubiquitin ligase complex

Class:Id	LiteratureReference:9705328
_displayName	IKKε-mediated tumorigenesis requires K63-linked polyubiquitination by a cIAP1/cIAP2/TRAF2 E3 ubiquitin ligase complex
_timestamp	2020-10-22 02:19:28
author	[Person:5362595] Zhou, Alicia Y [Person:5657673] Shen, Rhine R [Person:9652866] Kim, Eejung [Person:9705334] Lock, Ying J [Person:8934064] Xu, Ming [Person:2395999] Chen, Zhijian J [Person:2011584] Hahn, WC
created	[InstanceEdit:9705319] Shamovsky, Veronica, 2020-10-22
journal	Cell Rep
pages	724-33
pubMedIdentifier	23453969
title	IKKε-mediated tumorigenesis requires K63-linked polyubiquitination by a cIAP1/cIAP2/TRAF2 E3 ubiquitin ligase complex
volume	3
year	2013
(literatureReference)	[Complex:9730425] IKBKE:IKBKE [cytosol] [Homo sapiens] [CatalystActivityReference:9731425] ubiquitin protein ligase activity of TRAF2:BIRC2,BIRC3 [cytosol] IKKε-mediated tumorigenesis requires K63-linked polyubiquitination by a cIAP1/cIAP2/TRAF2 E3 ubiquitin ligase complex [BlackBoxEvent:9730433] K63-linked polyubiquitination of IKBKE by BIRC2,3:TRAF2 [Homo sapiens] [BlackBoxEvent:9823904] TBK1 is ubiquitinated within TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 [Homo sapiens] [BlackBoxEvent:9823939] IKKε (IKBKE) is ubiquitinated within the activated TLR4 [Homo sapiens] [BlackBoxEvent:9828200] TBK1 is ubiquitinated within TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR3 [Homo sapiens] [BlackBoxEvent:9830710] IKKε (IKBKE) is ubiquitinated within the activated TLR3 complex [Homo sapiens] [Summation:9705127] RIG‑I‑like receptors (RLRs) recognize RNAs from various RNA ... [Summation:9705310] Viral nucleic acids are sensed by cellular pattern-recogniti... [Summation:9705332] Viral nucleic acids are sensed by cellular pattern-recogniti... List all 21 refering instances
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No pathways have been reviewed or authored by IKKε-mediated tumorigenesis requires K63-linked polyubiquitination by a cIAP1/cIAP2/TRAF2 E3 ubiquitin ligase complex (9705328)