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Details on Person The ORF6, ORF8 and nucleocapsid proteins of SARS-CoV-2 inhibit type I interferon signaling pathway
| Class:Id | LiteratureReference:9705280 |
| _displayName | The ORF6, ORF8 and nucleocapsid proteins of SARS-CoV-2 inhibit type I interferon signaling pathway |
| _timestamp | 2020-10-22 02:15:51 |
| author | [Person:9705289] Li, Jin-Yan [Person:9705282] Liao, Ce-Heng [Person:9705284] Wang, Qiong [Person:9705290] Tan, Yong-Jun [Person:5696593] Luo, Rui [Person:9705296] Qiu, Ye [Person:9705300] Ge, Xing-Yi |
| created | [InstanceEdit:9705291] Shamovsky, Veronica, 2020-10-22 |
| journal | Virus Res |
| pages | 198074 |
| pubMedIdentifier | 32589897 |
| title | The ORF6, ORF8 and nucleocapsid proteins of SARS-CoV-2 inhibit type I interferon signaling pathway |
| volume | 286 |
| year | 2020 |
| (literatureReference) | [Reaction:9729437] SARS-CoV-2 N binds to TRIM25 [Homo sapiens] [Reaction:9729454] SARS-CoV-2 N protein binds STAT1, STAT2 [Homo sapiens] [Summation:9705279] Accessory open reading frame protein 6 (ORF6 or 6) of severe... [Summation:9708887] Accessory protein ORF6 (6) of severe acute respiratory syndr... [Summation:9717651] Antiviral innate immune response receptor RIG-I (also known ... [Summation:9729452] Type I interferon (IFN-I) immune signaling is dampened in CO... [RegulationReference:9757521] Negative regulation by 'KPNA2:6 [endoplasmic reticulum-Golgi intermediate compartment membrane]' SARS-CoV-2 nsp13, nsp14, nsp15 and orf6 function as potent interferon antagonists |
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