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Details on Person The ORF6, ORF8 and nucleocapsid proteins of SARS-CoV-2 inhibit type I interferon signaling pathway

Class:IdLiteratureReference:9705280
_displayNameThe ORF6, ORF8 and nucleocapsid proteins of SARS-CoV-2 inhibit type I interferon signaling pathway
_timestamp2020-10-22 02:15:51
author[Person:9705289] Li, Jin-Yan
[Person:9705282] Liao, Ce-Heng
[Person:9705284] Wang, Qiong
[Person:9705290] Tan, Yong-Jun
[Person:5696593] Luo, Rui
[Person:9705296] Qiu, Ye
[Person:9705300] Ge, Xing-Yi
created[InstanceEdit:9705291] Shamovsky, Veronica, 2020-10-22
journalVirus Res
pages198074
pubMedIdentifier32589897
titleThe ORF6, ORF8 and nucleocapsid proteins of SARS-CoV-2 inhibit type I interferon signaling pathway
volume286
year2020
(literatureReference)[Reaction:9729437] SARS-CoV-2 N binds to TRIM25 [Homo sapiens]
[Reaction:9729454] SARS-CoV-2 N protein binds STAT1, STAT2 [Homo sapiens]
[Summation:9705279] Accessory open reading frame protein 6 (ORF6 or 6) of severe...
[Summation:9708887] Accessory protein ORF6 (6) of severe acute respiratory syndr...
[Summation:9717651] Antiviral innate immune response receptor RIG-I (also known ...
[Summation:9729452] Type I interferon (IFN-I) immune signaling is dampened in CO...
[RegulationReference:9757521] Negative regulation by 'KPNA2:6 [endoplasmic reticulum-Golgi intermediate compartment membrane]' SARS-CoV-2 nsp13, nsp14, nsp15 and orf6 function as potent interferon antagonists
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