Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person The M2 muscarinic receptors (CHRM2) are expressed mainly in ...
| Class:Id | Summation:9705222 |
|---|---|
| _displayName | The M2 muscarinic receptors (CHRM2) are expressed mainly in ... |
| _timestamp | 2020-10-26 10:20:03 |
| created | [InstanceEdit:9705218] Jassal, Bijay, 2020-10-21 |
| modified | [InstanceEdit:9705496] Jassal, Bijay, 2020-10-26 |
| text | The M2 muscarinic receptors (CHRM2) are expressed mainly in the heart but also in many other tissues. Here, they act to slow the heart rate down by slowing the speed of depolarization. CHRM2 act via a Gi signalling pathway, which causes a decrease in intracellular cAMP leading to inhibitory-type effects (Caulfield & Birdsall 1998). Inhibition of CHRM2 for example by atropine or hyoscyamine will cause a rise in heart rate (Bagshaw et al. 1970). |
| (summation) | [Reaction:9704297] CHRM2 binds CHRM2 antagonists [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by The M2 muscarinic receptors (CHRM2) are expressed mainly in ... (9705222)
