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Details on Person NEK7 binds NLRP3

Class:Id	Reaction:9704722
_displayName	NEK7 binds NLRP3
_doRelease	FALSE
_timestamp	2020-10-14 20:34:17
created	[InstanceEdit:9704734] Shamovsky, Veronica, 2020-10-13
input	[EntityWithAccessionedSequence:2530599] NEK7 [cytosol] [Homo sapiens] [DefinedSet:1306878] NLRP3 elicitors:NLRP3 [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9704731] NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux [LiteratureReference:9704725] NEK7 Regulates NLRP3 Inflammasome Activation and Neuroinflammation Post-traumatic Brain Injury [LiteratureReference:9704735] NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component [LiteratureReference:9704873] Structural mechanism for NEK7-licensed activation of NLRP3 inflammasome
modified	[InstanceEdit:9704872] Shamovsky, Veronica, 2020-10-14
name	NEK7 binds NLRP3
output	[Complex:9704723] NLRP3 elicitors:NLRP3:NEK7 [cytosol] [Homo sapiens]
relatedSpecies	[Species:877180] Staphylococcus aureus
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9704737] R-HSA-9704722.1
summation	[Summation:9704715] The mitotic Ser/Thr kinase, known as never in mitosis A (NIM...
(hasEvent)	[Pathway:844456] The NLRP3 inflammasome [Homo sapiens]
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No pathways have been reviewed or authored by NEK7 binds NLRP3 (9704722)