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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person PALB2 L939W [nucleoplasm]

Class:IdEntityWithAccessionedSequence:9704417
_displayNamePALB2 L939W [nucleoplasm]
_timestamp2021-03-24 14:36:04
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9704416] Orlic-Milacic, Marija, 2020-10-09
crossReference[DatabaseIdentifier:9704418] COSMIC:COSV104552826
disease[Disease:1500689] cancer
[Disease:1500576] breast cancer
[Disease:1981182] lung squamous cell carcinoma
[Disease:1655499] prostate cancer
endCoordinate1186
hasModifiedResidue[ReplacedResidue:9704415] L-leucine 939 replaced with L-tryptophan
literatureReference[LiteratureReference:5685831] Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair
[LiteratureReference:9724157] Functional characterization of 84 PALB2 variants of uncertain significance
modified[InstanceEdit:9704426] Orlic-Milacic, Marija, 2020-10-09
[InstanceEdit:9724615] Orlic-Milacic, Marija, 2021-03-24
namePALB2 L939W
PALB2 Leu939Trp
referenceEntity[ReferenceGeneProduct:241569] UniProt:Q86YC2 PALB2 [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9704419] R-HSA-9704417.1
startCoordinate1
(hasMember)[CandidateSet:9704406] PALB2 mutants (BRCA2/RAD51/RAD51C binding) [nucleoplasm] [Homo sapiens]
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No pathways have been reviewed or authored by PALB2 L939W [nucleoplasm] (9704417)
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