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Details on Person GAB2 is presumed to be phosphorylated downstream of active F...

Class:IdSummation:9703418
_displayNameGAB2 is presumed to be phosphorylated downstream of active F...
_timestamp2020-10-06 15:18:22
created[InstanceEdit:9703419] Rothfels, Karen, 2020-10-06
textGAB2 is presumed to be phosphorylated downstream of active FLT3 fusion proteins, but this has not been directly demonstrated. ETV6-FLT3 is unable to transform primary myeloid cells from the bone marrow of Gab2-/- mice, implicating signaling through this pathway (Chonabayashi et al, 2013).
(summation)[Reaction:9703438] FLT3 fusions phosphorylate GAB2 [Homo sapiens]
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