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Details on Person p-Y FLT3 fusion dimers:GRB2 [cytosol]

Class:Id	Complex:9703378
_displayName	p-Y FLT3 fusion dimers:GRB2 [cytosol]
_timestamp	2020-10-06 15:17:56
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9703348] Rothfels, Karen, 2020-10-06
disease	[Disease:1500689] cancer
hasComponent	[CandidateSet:9703372] p-Y FLT3 fusion dimers [cytosol] [Homo sapiens] [EntityWithAccessionedSequence:74686] GRB2-1 [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9604770] Direct binding of Grb2 has an important role in the development of myeloproliferative disease induced by ETV6/FLT3
name	p-Y FLT3 fusion dimers:GRB2
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9703393] R-HSA-9703378.1
(hasComponent)	[Complex:9703349] p-Y FLT3 fusions:GRB2:SOS1 [cytosol] [Homo sapiens] [Complex:9703352] p-Y FLT3 fusions:GRB2:GAB2 [cytosol] [Homo sapiens] [Complex:9703356] p-Y FLT3 fusions:GRB2:p-Y GAB2 [cytosol] [Homo sapiens]
(input)	[Reaction:9703430] FLT3 fusions:GRB2 bind SOS1 [Homo sapiens] [Reaction:9703440] FLT3 fusions:GRB2 bind GAB2 [Homo sapiens]
(output)	[Reaction:9703442] Phosphorylated FLT3 fusions bind GRB2 [Homo sapiens]
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No pathways have been reviewed or authored by p-Y FLT3 fusion dimers:GRB2 [cytosol] (9703378)