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Details on Person p-Y FLT3 fusion dimers [cytosol]

Class:Id	CandidateSet:9703372
_displayName	p-Y FLT3 fusion dimers [cytosol]
_timestamp	2020-10-06 15:17:56
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9703348] Rothfels, Karen, 2020-10-06
disease	[Disease:1500689] cancer
hasCandidate	[Complex:9703366] TRIP11(2-1724)-p-4Y FLT3(594-993) fusion dimer [cytosol] [Homo sapiens] [Complex:9703363] ZMYM2(1-1057)-p-5Y FLT3(586-993) fusion dimer [cytosol] [Homo sapiens] [Complex:9703364] ZMYM2(1-1059)-p-4Y FLT3(594-993) fusion dimer [cytosol] [Homo sapiens] [Complex:9703374] MYO18A(1-1462)-p-4Y FLT3(595-993) fusion dimer [cytosol] [Homo sapiens] [Complex:9703375] ETV6(1-154insGSFILG)-p-6Y FLT3(573-993) fusion dimer [cytosol] [Homo sapiens] [Complex:9703353] ETV6(1-338insGCS)-p-6Y FLT3(573-993) fusion dimer [cytosol] [Homo sapiens] [Complex:9703362] ETV6(1-384)-p-6Y FLT3(573-993) fusion dimer [cytosol] [Homo sapiens]
hasMember	[Complex:9703373] ETV6(1-384)-p-3Y FLT3(659-1620) fusion dimer [cytosol] [Homo sapiens] [Complex:9703377] ETV6(1-301)-p-6Y FLT3(574-993) fusion dimer [cytosol] [Homo sapiens] [Complex:9703351] GOLGB1(1-2893)-p-5Y FLT3(591-993) fusion dimer [cytosol] [Homo sapiens] [Complex:9703376] SPTBN1(2-159)-p-6Y FLT3(570-993) fusion dimer [cytosol] [Homo sapiens]
name	p-Y FLT3 fusion dimers
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9703396] R-HSA-9703372.1
(activeUnit)	[CatalystActivity:9703426] protein tyrosine kinase activity of p-Y FLT3 fusions:GRB2:GAB2 [cytosol]
(hasComponent)	[Complex:9703359] p-Y FLT3 fusions:p-STAT5 [cytosol] [Homo sapiens] [Complex:9703378] p-Y FLT3 fusion dimers:GRB2 [cytosol] [Homo sapiens]
(input)	[BlackBoxEvent:9703435] FLT3 fusions activate STAT5 [Homo sapiens] [Reaction:9703442] Phosphorylated FLT3 fusions bind GRB2 [Homo sapiens]
(output)	[Reaction:9703437] FLT3 fusion dimers autophosphorylate [Homo sapiens]
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No pathways have been reviewed or authored by p-Y FLT3 fusion dimers [cytosol] (9703372)