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Details on Person SPTBN1(2-159)-FLT3(570-993) fusion [cytosol]

Class:Id	EntityWithAccessionedSequence:9703316
_displayName	SPTBN1(2-159)-FLT3(570-993) fusion [cytosol]
_timestamp	2020-10-06 15:16:30
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9703321] Rothfels, Karen, 2020-10-06
disease	[Disease:1500689] cancer [Disease:1247687] chronic myeloid leukemia
endCoordinate	159
hasModifiedResidue	[FragmentInsertionModification:9703288] Insertion of residues 570 to 993 at 160 from UniProt:P36888 FLT3
literatureReference	[LiteratureReference:9703191] A constitutively active SPTBN1-FLT3 fusion in atypical chronic myeloid leukemia is sensitive to tyrosine kinase inhibitors and immunotherapy
name	SPTBN1(2-159)-FLT3(570-993) fusion Spectrin beta chain, non-erythrocytic 1 SPTB2_HUMAN
referenceEntity	[ReferenceGeneProduct:64944] UniProt:Q01082 SPTBN1 [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9703339] R-HSA-9703316.1
startCoordinate	2
(hasComponent)	[Complex:9703361] SPTBN1(2-159)-FLT3570-993) fusion dimer [cytosol] [Homo sapiens]
(hasMember)	[CandidateSet:9703345] FLT3 fusion proteins [cytosol] [Homo sapiens]
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No pathways have been reviewed or authored by SPTBN1(2-159)-FLT3(570-993) fusion [cytosol] (9703316)