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Details on Person tamatinib-resistant FLT3 mutants [plasma membrane]

Class:Id	DefinedSet:9703004
_displayName	tamatinib-resistant FLT3 mutants [plasma membrane]
_timestamp	2020-10-03 01:52:31
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9703006] Rothfels, Karen, 2020-10-03
disease	[Disease:1500689] cancer
hasMember	[Complex:9682330] FLT3 D835A dimer [plasma membrane] [Homo sapiens] [Complex:9682338] FLT3 D835G dimer [plasma membrane] [Homo sapiens] [Complex:9682344] FLT3 D835N dimer [plasma membrane] [Homo sapiens] [Complex:9682356] FLT3 D835Y dimer [plasma membrane] [Homo sapiens] [Complex:9691983] FLT3 Y591_V592insVDFREYEYDH dimer [plasma membrane] [Homo sapiens]
literatureReference	[LiteratureReference:9702954] FLT3 activating mutations display differential sensitivity to multiple tyrosine kinase inhibitors
name	tamatinib-resistant FLT3 mutants
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9703012] R-HSA-9703004.1
(diseaseEntity)	[EntityFunctionalStatus:9703005] loss_of_function of tamatinib-resistant FLT3 mutants [plasma membrane]
(input)	[FailedReaction:9703008] tamatinib-resistant FLT3 mutants don't bind tamatinib [Homo sapiens]
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No pathways have been reviewed or authored by tamatinib-resistant FLT3 mutants [plasma membrane] (9703004)