Reactome: A Curated Pathway Database
THIS SITE IS USED FOR CURATION AND TESTING
IT IS NOT STABLE, IS LINKED TO AN INCOMPLETE DATA SET, AND IS NOT MONITORED FOR PERFORMANCE. WE STRONGLY RECOMMEND THE USE OF OUR PUBLIC SITE

Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.

Name Email address

Details on Person The multitargeted receptor tyrosine kinase inhibitor linifanib (ABT-869) induces apoptosis through an Akt and glycogen synthase kinase 3β-dependent pathway

Class:IdLiteratureReference:9702972
_displayNameThe multitargeted receptor tyrosine kinase inhibitor linifanib (ABT-869) induces apoptosis through an Akt and glycogen synthase kinase 3β-dependent pathway
_timestamp2020-10-03 01:51:24
author[Person:9702971] Hernandez-Davies, Jenny E
[Person:9702976] Zape, Joan P
[Person:9702973] Landaw, Elliot M
[Person:9702975] Tan, Xiaolin
[Person:9669093] Presnell, Ajia
[Person:9669218] Griffith, Diana
[Person:9669096] Heinrich, Michael C
[Person:9702974] Glaser, Keith B
[Person:9612300] Sakamoto, Kathleen M
created[InstanceEdit:9702970] Rothfels, Karen, 2020-10-03
journalMol. Cancer Ther.
pages949-59
pubMedIdentifier21471285
titleThe multitargeted receptor tyrosine kinase inhibitor linifanib (ABT-869) induces apoptosis through an Akt and glycogen synthase kinase 3β-dependent pathway
volume10
year2011
(literatureReference)[Reaction:9702508] FLT mutants bind type I TKIs [Homo sapiens]
[FailedReaction:9702997] linafinib-resistant FLT3 mutants don't bind linifanib [Homo sapiens]
[Pathway:9702998] linifanib-resistant FLT3 mutants [Homo sapiens]
[DefinedSet:9703018] linifanib-sensitive FLT3 mutants [plasma membrane] [Homo sapiens]
[Change default viewing format]
No pathways have been reviewed or authored by The multitargeted receptor tyrosine kinase inhibitor linifanib (ABT-869) induces apoptosis through an Akt and glycogen synthase kinase 3β-dependent pathway (9702972)