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Details on Person The following FLT3 mutants are resistant to sorafenib:
Class:Id Summation:9702923 _displayName The following FLT3 mutants are resistant to sorafenib:
_timestamp 2020-11-06 19:47:53 created [InstanceEdit:9702924] Rothfels, Karen, 2020-10-02 modified [InstanceEdit:9703028] Rothfels, Karen, 2020-10-03
[InstanceEdit:9706544] Rothfels, Karen, 2020-11-06
[InstanceEdit:9706546] Rothfels, Karen, 2020-11-06 text The following FLT3 mutants are resistant to sorafenib:
FLT3 A848P (von Bubnof et al, 2010)
FLT3 F691I Albers et al, 2013)
FLT3 F691L (Albers et al, 2013; Baker et al, 2013)
FLT3 Y842H (partial: Albers et al, 2013)
FLT3 D835A (Nguyen et al, 2017)
FLT3 D835F (Smith et al, 2012; 2013; 2015)
FLT3 D835H (Baker et al, 2013; Smith et al, 2015)
FLT3 D835V (Smith et al, 2012; 2013; 2015)
FLT3 D835Y (Moore et al, 2012; Nguyen et al, 2017; Smith et al, 2012; 2013; 2015)
(summation) [FailedReaction:9702623] sorafenib-resistant FLT3 mutants don't bind sorafenib [Homo sapiens]
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No pathways have been reviewed or authored by The following FLT3 mutants are resistant to sorafenib:
| Class:Id | Summation:9702923 |
|---|---|
| _displayName | The following FLT3 mutants are resistant to sorafenib: |
| _timestamp | 2020-11-06 19:47:53 |
| created | [InstanceEdit:9702924] Rothfels, Karen, 2020-10-02 |
| modified | [InstanceEdit:9703028] Rothfels, Karen, 2020-10-03 [InstanceEdit:9706544] Rothfels, Karen, 2020-11-06 [InstanceEdit:9706546] Rothfels, Karen, 2020-11-06 |
| text | The following FLT3 mutants are resistant to sorafenib: FLT3 A848P (von Bubnof et al, 2010) FLT3 F691I Albers et al, 2013) FLT3 F691L (Albers et al, 2013; Baker et al, 2013) FLT3 Y842H (partial: Albers et al, 2013) FLT3 D835A (Nguyen et al, 2017) FLT3 D835F (Smith et al, 2012; 2013; 2015) FLT3 D835H (Baker et al, 2013; Smith et al, 2015) FLT3 D835V (Smith et al, 2012; 2013; 2015) FLT3 D835Y (Moore et al, 2012; Nguyen et al, 2017; Smith et al, 2012; 2013; 2015) |
| (summation) | [FailedReaction:9702623] sorafenib-resistant FLT3 mutants don't bind sorafenib [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by The following FLT3 mutants are resistant to sorafenib: