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Details on Person The effects of lestaurtinib (CEP701) and PKC412 on primary AML blasts: the induction of cytotoxicity varies with dependence on FLT3 signaling in both FLT3-mutated and wild-type cases

Class:Id	LiteratureReference:9702890
_displayName	The effects of lestaurtinib (CEP701) and PKC412 on primary AML blasts: the induction of cytotoxicity varies with dependence on FLT3 signaling in both FLT3-mutated and wild-type cases
_timestamp	2020-10-02 17:59:31
author	[Person:9702886] Knapper, Steven [Person:9702888] Mills, Kenneth I [Person:9702889] Gilkes, Amanda F [Person:9702883] Austin, Steve J [Person:9702885] Walsh, Val [Person:9702887] Burnett, Alan K
created	[InstanceEdit:9702884] Rothfels, Karen, 2020-10-02
journal	Blood
pages	3494-503
pubMedIdentifier	16868253
title	The effects of lestaurtinib (CEP701) and PKC412 on primary AML blasts: the induction of cytotoxicity varies with dependence on FLT3 signaling in both FLT3-mutated and wild-type cases
volume	108
year	2006
(literatureReference)	[DefinedSet:9699520] lestaurtinib-sensitive FLT3 mutants [plasma membrane] [Homo sapiens] [DefinedSet:9699529] midostaurin-sensitive FLT3 mutants [plasma membrane] [Homo sapiens] [DefinedSet:9699536] midostaurin-resistant FLT3 mutants [plasma membrane] [Homo sapiens] [Reaction:9702508] FLT mutants bind type I TKIs [Homo sapiens] [FailedReaction:9702601] midostaurin-resistant FLT3 mutants don't bind midostaurin [Homo sapiens]
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