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Details on Person TFG(1-138)-p-7Y-ALK(1058-1620) fusion [cytosol]

Class:Id	EntityWithAccessionedSequence:9702019
_displayName	TFG(1-138)-p-7Y-ALK(1058-1620) fusion [cytosol]
_timestamp	2023-03-30 17:41:38
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9702020] Rothfels, Karen, 2020-09-28
crossReference	[DatabaseIdentifier:9700456] COSMIC:COSF424
disease	[Disease:9699595] anaplastic large cell lymphoma [Disease:1500689] cancer
endCoordinate	138
hasModifiedResidue	[FragmentInsertionModification:9699849] Insertion of residues 1058 to 1620 at 139 from UniProt:Q9UM73 ALK [ModifiedResidue:9699796] O4'-phospho-L-tyrosine at 1096 [ModifiedResidue:9699868] O4'-phospho-L-tyrosine at 1278 [ModifiedResidue:9699844] O4'-phospho-L-tyrosine at 1282 [ModifiedResidue:9699911] O4'-phospho-L-tyrosine at 1283 [ModifiedResidue:9699876] O4'-phospho-L-tyrosine at 1359 [ModifiedResidue:9699886] O4'-phospho-L-tyrosine at 1507 [ModifiedResidue:9699803] O4'-phospho-L-tyrosine at 1604
literatureReference	[LiteratureReference:9699785] TRK-fused gene (TFG) is a new partner of ALK in anaplastic large cell lymphoma producing two structurally different TFG-ALK translocations
modified	[InstanceEdit:9832399] Orlic-Milacic, Marija, 2023-03-30
name	TFG(1-138)-p-7Y-ALK(1058-1620) fusion Protein TFG TFG_HUMAN TFGs-ALK
referenceEntity	[ReferenceGeneProduct:154850] UniProt:Q92734 TFG [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9702021] R-HSA-9702019.2
startCoordinate	1
(hasComponent)	[Complex:9702022] TFG(1-138)-p-7Y ALK(1058-1620) fusion dimer [cytosol] [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9905505] Update Tracker - [EntityWithAccessionedSequence:9702019] TFG(1-138)-p-7Y-ALK(1058-1620) fusion [cytosol] - v85:[modifyName]
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No pathways have been reviewed or authored by TFG(1-138)-p-7Y-ALK(1058-1620) fusion [cytosol] (9702019)