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Details on Person AcK685-p-Y705,S727 STAT3 and SIN3A bind the PDRM1 promoter

Class:IdReaction:9701549
_displayNameAcK685-p-Y705,S727 STAT3 and SIN3A bind the PDRM1 promoter
_doReleaseTRUE
_timestamp2021-05-04 17:33:52
authored[InstanceEdit:9725664] Rothfels, Karen, 2021-03-30
compartment[Compartment:7660] nucleoplasm
created[InstanceEdit:9701550] Rothfels, Karen, 2020-09-26
edited[InstanceEdit:9725664] Rothfels, Karen, 2021-03-30
input[Complex:9701465] AcK685- p-Y705,S727-STAT3 dimer [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:351657] SIN3A [nucleoplasm] [Homo sapiens]
[EntityWithAccessionedSequence:6804192] PRDM1 Gene [nucleoplasm] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9701314] The Transcriptional Regulator Sin3A Contributes to the Oncogenic Potential of STAT3
[LiteratureReference:9702103] PRDM1/BLIMP1: a tumor suppressor gene in B and T cell lymphomas
modified[InstanceEdit:9702111] Rothfels, Karen, 2020-09-29
[InstanceEdit:9729590] Rothfels, Karen, 2021-04-30
[InstanceEdit:9729687] Rothfels, Karen, 2021-05-03
[InstanceEdit:9729893] Rothfels, Karen, 2021-05-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
nameAcK685-p-Y705,S727 STAT3 and SIN3A bind the PDRM1 promoter
output[Complex:9701467] SIN3A:AcK685,p-Y705,p-S727 STAT3 dimer:PRDM1 gene [nucleoplasm] [Homo sapiens]
precedingEvent
releaseDate2021-06-09
reviewed[InstanceEdit:9729891] Inghirami, Giorgio, 2021-05-04
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9701552] R-HSA-9701549.2
summation[Summation:9701502] Acetylated, phosphorylated STAT3 and SIN3A bind to the PRDM1...
(hasEvent)[Pathway:9701898] STAT3 nuclear events downstream of ALK signaling [Homo sapiens]
(precedingEvent)[BlackBoxEvent:9701548] PRDM1 gene expression downstream of ALK signaling [Homo sapiens]
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No pathways have been reviewed or authored by AcK685-p-Y705,S727 STAT3 and SIN3A bind the PDRM1 promoter (9701549)