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Details on Person p-Y705, p-S727 STAT3 dimer translocates to the nucleus

Class:Id	BlackBoxEvent:9701529
_displayName	p-Y705, p-S727 STAT3 dimer translocates to the nucleus
_doRelease	TRUE
_timestamp	2021-05-04 17:36:56
authored	[InstanceEdit:9725664] Rothfels, Karen, 2021-03-30
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:9701528] Rothfels, Karen, 2020-09-26
edited	[InstanceEdit:9725664] Rothfels, Karen, 2021-03-30
input	[Complex:9701454] p-Y705,S727-STAT3 dimer [cytosol] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:9701396] Revisiting STAT3 signalling in cancer: new and unexpected biological functions [LiteratureReference:9701333] STAT3: a multifaceted oncoprotein
modified	[InstanceEdit:9729590] Rothfels, Karen, 2021-04-30 [InstanceEdit:9729893] Rothfels, Karen, 2021-05-04 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	p-Y705, p-S727 STAT3 dimer translocates to the nucleus
output	[Complex:9701457] p-Y705,S727-STAT3 dimer [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:9701525] p-Y705,S727-STAT3 dimerizes [Homo sapiens] [BlackBoxEvent:9701524] STAT3 is phosphorylated downstream of active ALK [Homo sapiens]
releaseDate	2021-06-09
reviewed	[InstanceEdit:9729891] Inghirami, Giorgio, 2021-05-04
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9701533] R-HSA-9701529.2
summation	[Summation:9701504] After phosphorylation of Y705 (and in some cases, of S727 in...
(hasEvent)	[Pathway:201556] Signaling by ALK [Homo sapiens]
(precedingEvent)	[Reaction:9701531] p-Y705,S727 STAT3 is acetylated [Homo sapiens] [Reaction:9701534] p-Y705, S727 STAT3 dimer binds HIF1A gene [Homo sapiens] [Reaction:9701537] p-Y705, S727 STAT3 dimer binds CD274 gene [Homo sapiens] [Reaction:9909609] STAT3 dimer binding to CD274 gene [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9853240] Update Tracker - [BlackBoxEvent:9701529] p-Y705, p-S727 STAT3 dimer translocates to the nucleus - v87:[modifyText]
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