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Details on Person Acetylated, phosphorylated STAT3 and SIN3A bind to the PRDM1...

Class:IdSummation:9701502
_displayNameAcetylated, phosphorylated STAT3 and SIN3A bind to the PRDM1...
_timestamp2020-09-29 14:52:54
created[InstanceEdit:9701501] Rothfels, Karen, 2020-09-26
modified[InstanceEdit:9702113] Rothfels, Karen, 2020-09-29
textAcetylated, phosphorylated STAT3 and SIN3A bind to the PRDM1 promoter downstream of ALK signaling as assessed by ChIP in NPM-ALK cells (Gambi et al, 2019). Binding contributes to transcriptional repression of PRDM1, also known as BLIMP1, a transcription factor with roles in innate and adaptive immune response in B and T cells (reviewed in Boi et al, 2015).
(summation)[Reaction:9701549] AcK685-p-Y705,S727 STAT3 and SIN3A bind the PDRM1 promoter [Homo sapiens]
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