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Query author contributions in Reactome

Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.

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Details on Person ALK L1198F [plasma membrane]

Class:IdEntityWithAccessionedSequence:9701434
_displayNameALK L1198F [plasma membrane]
_timestamp2020-09-28 00:26:03
compartment[Compartment:876] plasma membrane
created[InstanceEdit:9701436] Rothfels, Karen, 2020-09-26
crossReference[DatabaseIdentifier:9701285] COSMIC:COSM9311666
[DatabaseIdentifier:9701289] COSMIC:COSV66556391
disease[Disease:1981182] lung squamous cell carcinoma
[Disease:6802256] thyroid carcinoma
endCoordinate1620
hasModifiedResidue[ReplacedResidue:9701415] L-leucine 1198 replaced with L-phenylalanine
literatureReference[LiteratureReference:9700350] The ALK inhibitor ceritinib overcomes crizotinib resistance in non-small cell lung cancer
[LiteratureReference:9701769] Anaplastic thyroid cancers harbor novel oncogenic mutations of the ALK gene
modified[InstanceEdit:9701908] Rothfels, Karen, 2020-09-28
nameALK L1198F
ALK tyrosine kinase receptor
ALK_HUMAN
referenceEntity[ReferenceGeneProduct:49894] UniProt:Q9UM73 ALK [Homo sapiens]
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9701445] R-HSA-9701434.1
startCoordinate19
(hasComponent)[Complex:9701829] ALK L1198F dimer [plasma membrane] [Homo sapiens]
(hasMember)[CandidateSet:9700083] kinase domain ALK mutants [plasma membrane] [Homo sapiens]
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No pathways have been reviewed or authored by ALK L1198F [plasma membrane] (9701434)
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