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Details on Person Role of ERK-BIM and STAT3-survivin signaling pathways in ALK inhibitor-induced apoptosis in EML4-ALK-positive lung cancer

Class:IdLiteratureReference:9701376
_displayNameRole of ERK-BIM and STAT3-survivin signaling pathways in ALK inhibitor-induced apoptosis in EML4-ALK-positive lung cancer
_timestamp2020-09-26 21:52:57
author[Person:9701310] Takezawa, Ken
[Person:9701312] Okamoto, Isamu
[Person:2023767] Nishio, K
[Person:8852956] Jänne, Pasi A
[Person:9701395] Nakagawa, Kazuhiko
created[InstanceEdit:9701293] Rothfels, Karen, 2020-09-26
journalClin. Cancer Res.
pages2140-8
pubMedIdentifier21415216
titleRole of ERK-BIM and STAT3-survivin signaling pathways in ALK inhibitor-induced apoptosis in EML4-ALK-positive lung cancer
volume17
year2011
(literatureReference)[Reaction:9700179] Ligand-independent dimerization of ALK fusions [Homo sapiens]
[Reaction:9712079] ALK mutants bind STAT3 [Homo sapiens]
[EntityWithAccessionedSequence:9699812] EML4(1-496)-ALK(1058-1620) fusion [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:9699813] EML4(1-223)insKMSTREKNSQV-ALK(1059-1620) fusion [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:9699862] EML4(1-223)-ALK(1059-1620) fusion [cytosol] [Homo sapiens]
[CandidateSet:9700080] ALK fusion proteins [cytosol] [Homo sapiens]
[CandidateSet:9711929] PI3K-binding ALK mutants [cytosol] [Homo sapiens]
[CandidateSet:9711944] STAT3-activating ALK mutants [cytosol] [Homo sapiens]
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