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Details on Person Stat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target

Class:IdLiteratureReference:9701357
_displayNameStat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target
_timestamp2020-09-26 21:52:52
author[Person:9667884] Chiarle, Roberto
[Person:9701329] Simmons, William J
[Person:9701403] Cai, Honjying
[Person:9701367] Dhall, Girish
[Person:9701399] Zamo, Alberto
[Person:3222419] Raz, Regina
[Person:9701359] Karras, James G
[Person:9027584] Levy, David E
[Person:9648424] Inghirami, Giorgio
created[InstanceEdit:9701293] Rothfels, Karen, 2020-09-26
journalNat. Med.
pages623-9
pubMedIdentifier15895073
titleStat3 is required for ALK-mediated lymphomagenesis and provides a possible therapeutic target
volume11
year2005
(literatureReference)[BlackBoxEvent:9701524] STAT3 is phosphorylated downstream of active ALK [Homo sapiens]
[Reaction:9712079] ALK mutants bind STAT3 [Homo sapiens]
[BlackBoxEvent:9850958] pY-STAT3 dimer translocates to the nucleus downstream of ALK mutants [Homo sapiens]
[BlackBoxEvent:9851142] TYK2-dependent STAT1 and STAT3 phosphorylation [Homo sapiens]
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