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Details on Person Restoration of shp1 expression by 5-AZA-2'-deoxycytidine is associated with downregulation of JAK3/STAT3 signaling in ALK-positive anaplastic large cell lymphoma

Class:Id	LiteratureReference:9701348
_displayName	Restoration of shp1 expression by 5-AZA-2'-deoxycytidine is associated with downregulation of JAK3/STAT3 signaling in ALK-positive anaplastic large cell lymphoma
_timestamp	2020-09-26 21:52:49
author	[Person:5322931] Han, Y [Person:9701320] Amin, H M [Person:9701296] Frantz, C [Person:9701373] Franko, B [Person:5433010] Lee, J [Person:9675747] Lin, Q [Person:9701380] Lai, R
created	[InstanceEdit:9701293] Rothfels, Karen, 2020-09-26
journal	Leukemia
pages	1602-9
pubMedIdentifier	16871283
title	Restoration of shp1 expression by 5-AZA-2'-deoxycytidine is associated with downregulation of JAK3/STAT3 signaling in ALK-positive anaplastic large cell lymphoma
volume	20
year	2006
(literatureReference)	[Reaction:9701485] Active ALK binds JAK3 [Homo sapiens] [Reaction:9701488] Active ALK phosphorylates JAK3 [Homo sapiens] [Reaction:9701507] PTPN6 dephosphorylates JAK3 [Homo sapiens] [BlackBoxEvent:9701524] STAT3 is phosphorylated downstream of active ALK [Homo sapiens] [Reaction:9712079] ALK mutants bind STAT3 [Homo sapiens] [BlackBoxEvent:9850958] pY-STAT3 dimer translocates to the nucleus downstream of ALK mutants [Homo sapiens]
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No pathways have been reviewed or authored by Restoration of shp1 expression by 5-AZA-2'-deoxycytidine is associated with downregulation of JAK3/STAT3 signaling in ALK-positive anaplastic large cell lymphoma (9701348)