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Details on Person Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3

Class:Id	LiteratureReference:9701292
_displayName	Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3
_timestamp	2020-09-26 21:52:34
author	[Person:9701390] Marzec, Michal [Person:9015455] Kasprzycka, Monika [Person:9701344] Ptasznik, Andrzej [Person:9701385] Wlodarski, Pawel [Person:8858043] Zhang, Qian [Person:9701309] Odum, Niels [Person:9701386] Wasik, Mariusz A
created	[InstanceEdit:9701293] Rothfels, Karen, 2020-09-26
journal	Lab. Invest.
pages	1544-54
pubMedIdentifier	16170336
title	Inhibition of ALK enzymatic activity in T-cell lymphoma cells induces apoptosis and suppresses proliferation and STAT3 phosphorylation independently of Jak3
volume	85
year	2005
(literatureReference)	[Reaction:9701485] Active ALK binds JAK3 [Homo sapiens] [BlackBoxEvent:9701524] STAT3 is phosphorylated downstream of active ALK [Homo sapiens] [Reaction:9712079] ALK mutants bind STAT3 [Homo sapiens] [BlackBoxEvent:9850958] pY-STAT3 dimer translocates to the nucleus downstream of ALK mutants [Homo sapiens]
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