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Details on Person TRPV1 transports Ca2+ from extracellular region to cytosol

Class:Id	Reaction:9701141
_displayName	TRPV1 transports Ca2+ from extracellular region to cytosol
_doRelease	TRUE
_timestamp	2020-09-24 14:01:41
authored	[InstanceEdit:3295578] Jassal, Bijay, 2013-04-17
catalystActivity	[CatalystActivity:9701134] voltage-gated calcium channel activity of TRPV1 [plasma membrane]
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane [Compartment:984] extracellular region
created	[InstanceEdit:9701139] Jassal, Bijay, 2020-09-24
edited	[InstanceEdit:9701139] Jassal, Bijay, 2020-09-24
input	[SimpleEntity:74112] Ca2+ [extracellular region]
isChimeric	FALSE
literatureReference	[LiteratureReference:3296352] International Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel family [LiteratureReference:3296348] Structure-functional intimacies of transient receptor potential channels [LiteratureReference:9701135] The tissue distribution and functional characterization of human VR1 [LiteratureReference:9701106] Cloning and functional expression of a human orthologue of rat vanilloid receptor-1
modified	[InstanceEdit:9701143] Jassal, Bijay, 2020-09-24 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TRPV1 transports Ca2+ from extracellular region to cytosol
output	[SimpleEntity:74016] Ca2+ [cytosol]
regulatedBy	[PositiveRegulation:5357877] Positive regulation by 'p-S-RIPK1:p-S199,227-RIPK3:p-T357,S358-MLKL oligomer [cytosol]'
regulationReference	[RegulationReference:9642552] Positive regulation by 'p-S-RIPK1:p-S199,227-RIPK3:p-T357,S358-MLKL oligomer [cytosol]' Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis
releaseDate	2013-09-18
reviewed	[InstanceEdit:3901316] He, Lei, 2013-07-16
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9701142] R-HSA-9701141.2
summation	[Summation:9701132] All functionally characterized TRP channels are permeable to...
(hasEvent)	[Pathway:3295583] TRP channels [Homo sapiens]
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No pathways have been reviewed or authored by TRPV1 transports Ca2+ from extracellular region to cytosol (9701141)