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Details on Person BAP1 binds BRCA1:BARD1 heterodimer

Class:Id	Reaction:9701003
_displayName	BAP1 binds BRCA1:BARD1 heterodimer
_doRelease	TRUE
_timestamp	2020-11-10 17:47:24
authored	[InstanceEdit:9702562] Orlic-Milacic, Marija, 2020-09-30
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9701005] Orlic-Milacic, Marija, 2020-09-23
edited	[InstanceEdit:9706872] Orlic-Milacic, Marija, 2020-11-09
input	[EntityWithAccessionedSequence:5689665] BAP1 [nucleoplasm] [Homo sapiens] [Complex:5659802] BRCA1:BARD1 [nucleoplasm] [Homo sapiens]
isChimeric	FALSE
literatureReference	[LiteratureReference:5689660] BRCA1-associated protein 1 interferes with BRCA1/BARD1 RING heterodimer activity
modified	[InstanceEdit:9701017] Orlic-Milacic, Marija, 2020-09-23 [InstanceEdit:9707068] Orlic-Milacic, Marija, 2020-11-10 [InstanceEdit:9707093] Orlic-Milacic, Marija, 2020-11-10 [InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	BAP1 binds BRCA1:BARD1 heterodimer
output	[Complex:9701007] BRCA1:BARD1:BAP1 [nucleoplasm] [Homo sapiens]
precedingEvent	[Reaction:5659781] BRCA1 forms a heterodimer with BARD1 [Homo sapiens]
releaseDate	2020-12-08
reviewed	[InstanceEdit:9706944] Baer, Richard J, 2020-11-04
reviewStatus	[ReviewStatus:9821382] five stars
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9701010] R-HSA-9701003.2
summation	[Summation:9701015] BAP1 binds to the BRCA1:BARD1 complex mainly through interac...
(hasEvent)	[Pathway:5693565] Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks [Homo sapiens]
(precedingEvent)	[Reaction:9700998] BAP1 disrupts the BRCA1:BARD1 heterodimer [Homo sapiens]
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No pathways have been reviewed or authored by BAP1 binds BRCA1:BARD1 heterodimer (9701003)