Query author contributions in Reactome
Reactome depends on collaboration between our curation team and outside experts to assemble and peer-review its pathway modules. The integration of ORCID within Reactome enables us to meet a key challenge with authoring, curating and reviewing biological information by incentivizing and crediting the external experts that contribute their expertise and time to the Reactome curation process. More information is available at ORCID and Reactome.
If you have an ORCID ID that is not listed on this page, please forward this information to us and we will update your Reactome pathway records.
Details on Person Based on studies with the oncogenic fusion protein NPM-ALK, ...
| Class:Id | Summation:9700644 |
|---|---|
| _displayName | Based on studies with the oncogenic fusion protein NPM-ALK, ... |
| _timestamp | 2020-09-16 05:25:57 |
| created | [InstanceEdit:9700663] Rothfels, Karen, 2020-09-16 |
| text | Based on studies with the oncogenic fusion protein NPM-ALK, SRC (and potentially other SRC-family members) binds to activated ALK receptor. Binding depends on tyrosine residue 1358 and ALK kinase activity, identifying pY1358 as the SRC-binding site (Cussac et al, 2004). SRC signaling downstream of ALK contributes to cellular proliferation (Cussac et al, 2004; reviewed in Chiarle et al, 2008; Palmer et al, 2009). |
| (summation) | [Reaction:9700648] Active ALK binds SRC [Homo sapiens] |
| [Change default viewing format] | |
No pathways have been reviewed or authored by Based on studies with the oncogenic fusion protein NPM-ALK, ... (9700644)
