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Details on Person STRN(1-137)-p-7Y-ALK(1058-1620) fusion [cytosol]

Class:Id	EntityWithAccessionedSequence:9700467
_displayName	STRN(1-137)-p-7Y-ALK(1058-1620) fusion [cytosol]
_timestamp	2023-03-30 17:41:36
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9700471] Rothfels, Karen, 2020-09-16
disease	[Disease:8853117] lung adenocarcinoma [Disease:6802256] thyroid carcinoma
endCoordinate	137
hasModifiedResidue	[FragmentInsertionModification:9700449] Insertion of residues 1058 to 1620 at 138 from UniProt:Q9UM73 ALK [ModifiedResidue:9699796] O4'-phospho-L-tyrosine at 1096 [ModifiedResidue:9699868] O4'-phospho-L-tyrosine at 1278 [ModifiedResidue:9699844] O4'-phospho-L-tyrosine at 1282 [ModifiedResidue:9699911] O4'-phospho-L-tyrosine at 1283 [ModifiedResidue:9699876] O4'-phospho-L-tyrosine at 1359 [ModifiedResidue:9699886] O4'-phospho-L-tyrosine at 1507 [ModifiedResidue:9699803] O4'-phospho-L-tyrosine at 1604
literatureReference	[LiteratureReference:9700342] Identification of recurrent FGFR3 fusion genes in lung cancer through kinome-centred RNA sequencing [LiteratureReference:9711822] Identification of a recurrent STRN/ALK fusion in thyroid carcinomas
modified	[InstanceEdit:9702045] Rothfels, Karen, 2020-09-28 [InstanceEdit:9711951] Rothfels, Karen, 2021-01-13 [InstanceEdit:9832399] Orlic-Milacic, Marija, 2023-03-30
name	STRN(1-137)-p-7Y-ALK(1058-1620) fusion Striatin
referenceEntity	[ReferenceGeneProduct:65240] UniProt:O43815 STRN [Homo sapiens]
species	[Species:48887] Homo sapiens
stableIdentifier	[StableIdentifier:9700494] R-HSA-9700467.2
startCoordinate	1
(hasComponent)	[Complex:9700524] STRN(1-137)-p-7Y ALK(1058-1620) fusion dimer [cytosol] [Homo sapiens]
(updatedInstance)	[_UpdateTracker:9905439] Update Tracker - [EntityWithAccessionedSequence:9700467] STRN(1-137)-p-7Y-ALK(1058-1620) fusion [cytosol] - v85:[modifyName]
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No pathways have been reviewed or authored by STRN(1-137)-p-7Y-ALK(1058-1620) fusion [cytosol] (9700467)