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Details on Person Oncogenic mutations of ALK kinase in neuroblastoma

Class:IdLiteratureReference:9700372
_displayNameOncogenic mutations of ALK kinase in neuroblastoma
_timestamp2020-09-16 05:14:57
author[Person:9700383] Chen, Yuyan
[Person:9700371] Takita, Junko
[Person:9648137] Choi, Young Lim
[Person:9700366] Kato, Motohiro
[Person:9700362] Ohira, Miki
[Person:8865933] Sanada, Masashi
[Person:9647295] Wang, Lili
[Person:9648143] Soda, Manabu
[Person:4640987] Kikuchi, Akira
[Person:5625238] Igarashi, Takashi
[Person:3215266] Nakagawara, Akira
[Person:9700312] Hayashi, Yasuhide
[Person:5368311] Mano, Hiroyuki
[Person:8865964] Ogawa, Seishi
created[InstanceEdit:9700359] Rothfels, Karen, 2020-09-16
journalNature
pages971-4
pubMedIdentifier18923524
titleOncogenic mutations of ALK kinase in neuroblastoma
volume455
year2008
(literatureReference)[Summation:9723305] Oncogenic point mutations in ALK promote ligand-independent ...
[EntityWithAccessionedSequence:9700435] ALK K1062M [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:9700473] p-7Y ALK K1062M [plasma membrane] [Homo sapiens]
[CandidateSet:9711929] PI3K-binding ALK mutants [cytosol] [Homo sapiens]
[CandidateSet:9711944] STAT3-activating ALK mutants [cytosol] [Homo sapiens]
[CandidateSet:9713538] SHC-binding ALK mutant dimers [cytosol] [Homo sapiens]
[EntityWithAccessionedSequence:9723874] ALK T1087I [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:9723885] p-7Y ALK T1087I [plasma membrane] [Homo sapiens]
[Reaction:201510] PI3K synthesizes PIP3 downstream of ALK [Homo sapiens]
[Reaction:9700184] Ligand-independent dimerization of point mutants of ALK [Homo sapiens]
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