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Details on Person The ALK inhibitor ceritinib overcomes crizotinib resistance in non-small cell lung cancer

Class:IdLiteratureReference:9700350
_displayNameThe ALK inhibitor ceritinib overcomes crizotinib resistance in non-small cell lung cancer
_timestamp2020-09-16 05:14:52
author[Person:9700335] Friboulet, Luc
[Person:9699663] Li, Nanxin
[Person:6806119] Katayama, Ryohei
[Person:9699661] Lee, Christian C
[Person:9700406] Gainor, Justin F
[Person:9700392] Crystal, Adam S
[Person:9699662] Michellys, Pierre-Yves
[Person:9700367] Awad, Mark M
[Person:9700346] Yanagitani, Noriko
[Person:114225] Kim, S
[Person:9700401] Pferdekamper, AnneMarie C
[Person:2404150] Li, Jie
[Person:5340456] Kasibhatla, Shailaja
[Person:9700328] Sun, Frank
[Person:9699669] Sun, Xiuying
[Person:9699664] Hua, Su
[Person:5340472] McNamara, Peter
[Person:9700376] Mahmood, Sidra
[Person:9700347] Lockerman, Elizabeth L
[Person:9700375] Fujita, Naoya
[Person:9700319] Nishio, Makoto
[Person:5340448] Harris, Jennifer L
[Person:9700355] Shaw, Alice T
[Person:9029753] Engelman, Jeffrey A
created[InstanceEdit:9700359] Rothfels, Karen, 2020-09-16
journalCancer Discov
pages662-673
pubMedIdentifier24675041
titleThe ALK inhibitor ceritinib overcomes crizotinib resistance in non-small cell lung cancer
volume4
year2014
(literatureReference)[Reaction:9700131] ALK mutants bind type I TKIs [Homo sapiens]
[FailedReaction:9700658] ceritinib-resistant ALK mutants don't bind ceritinib [Homo sapiens]
[FailedReaction:9715357] crizotinib-resistant ALK mutants don't bind crizotinib [Homo sapiens]
[DefinedSet:9700528] ceritinib-sensitive ALK mutants [plasma membrane] [Homo sapiens]
[DefinedSet:9700553] ceritinib-resistant ALK mutants [plasma membrane] [Homo sapiens]
[DefinedSet:9700564] crizotinib resistant ALK mutants [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:9701426] ALK S1206Y [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:9701427] ALK G1269A [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:9701433] ALK C1156Y [plasma membrane] [Homo sapiens]
[EntityWithAccessionedSequence:9701434] ALK L1198F [plasma membrane] [Homo sapiens]
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No pathways have been reviewed or authored by The ALK inhibitor ceritinib overcomes crizotinib resistance in non-small cell lung cancer (9700350)