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Query author contributions in Reactome

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Details on Person Active ALK binds PLCG1

Class:IdReaction:9700149
_displayNameActive ALK binds PLCG1
_doReleaseTRUE
_timestamp2023-11-09 18:37:05
authored[InstanceEdit:9725664] Rothfels, Karen, 2021-03-30
compartment[Compartment:876] plasma membrane
created[InstanceEdit:9700150] Rothfels, Karen, 2020-09-14
edited[InstanceEdit:9725664] Rothfels, Karen, 2021-03-30
input[SimpleEntity:179838] PI(3,4,5)P3 [plasma membrane]
[EntityWithAccessionedSequence:167682] PLCG1 [plasma membrane] [Homo sapiens]
[CandidateSet:9850879] Active ALK dimer [plasma membrane] [Homo sapiens]
isChimericFALSE
literatureReference[LiteratureReference:9699741] Nucleophosmin-anaplastic lymphoma kinase of large-cell anaplastic lymphoma is a constitutively active tyrosine kinase that utilizes phospholipase C-gamma to mediate its mitogenicity
[LiteratureReference:9843020] Fusion tyrosine kinase mediated signalling pathways in the transformation of haematopoietic cells
[LiteratureReference:9667881] The anaplastic lymphoma kinase in the pathogenesis of cancer
modified[InstanceEdit:9729590] Rothfels, Karen, 2021-04-30
[InstanceEdit:9729893] Rothfels, Karen, 2021-05-04
[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
[InstanceEdit:9850956] Rothfels, Karen, 2023-10-12
[InstanceEdit:9853042] Rothfels, Karen, 2023-11-09
nameActive ALK binds PLCG1
output[Complex:9699982] Active ALK:PLCG1 [plasma membrane] [Homo sapiens]
precedingEvent
previousReviewStatus[ReviewStatus:9821384] two stars
releaseDate2021-06-09
reviewed[InstanceEdit:9729891] Inghirami, Giorgio, 2021-05-04
[InstanceEdit:9852935] Turner, Suzanne, 2023-11-08
reviewStatus[ReviewStatus:9821382] five stars
species[Species:48887] Homo sapiens
stableIdentifier[StableIdentifier:9700151] R-HSA-9700149.3
structureModified[InstanceEdit:9850956] Rothfels, Karen, 2023-10-12
summation[Summation:9700148] Based on studies with the oncogenic NPM-ALK fusion, ALK is p...
(hasEvent)[Pathway:201556] Signaling by ALK [Homo sapiens]
(precedingEvent)[Reaction:9700171] Active ALK phosphorylates PLCG1 [Homo sapiens]
(updatedInstance)[_UpdateTracker:9853234] Update Tracker - [Reaction:9700149] Active ALK binds PLCG1 - v87:[addLiteratureReference, add_removeInput, modifyText]
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No pathways have been reviewed or authored by Active ALK binds PLCG1 (9700149)